Correction to: Nationwide randomised trial evaluating elective neck dissection for early stage oral cancer (SEND study) with meta-analysis and concurrent real-world cohort
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Authors
Grew, Nick
Issue Date
2021-11-23
Journal
Type
Article
Keywords
Correction
Disease-free survival
Elective surgery
Mouth cancer
Mouth neoplasms
Neck
Neck dissection
Neoplasm staging
Oral cancer
Squamous cell carcinoma
Treatment outcome
Disease-free survival
Elective surgery
Mouth cancer
Mouth neoplasms
Neck
Neck dissection
Neoplasm staging
Oral cancer
Squamous cell carcinoma
Treatment outcome
Journal Title
British Journal of Cancer
Volume
Issue
Begin page
End page
Abstract
The original version of this article unfortunately contained a mistake. A correction is needed for one of the trials in the meta-analysis (Fig. 3). For Fakih et al. 1989, the relative risk of death (used as an estimate of the overall survival hazard ratio; as the authors did with other trials that did not report hazard ratios directly) was calculated using 8 deaths among 30 patients who had neck dissection versus 16 deaths among 40 patients who had resection only (RR = 0.67). The authors have since noted that there were 9 deaths among the 30 patients, yielding RR = 0.75 95% CI: 0.39–1.46. This trial had a small weight in the meta-analysis, so the corrected pooled hazard ratio across all 5 trials is now RR = 0.70 (95% CI: 0.55–0.88); almost the same as that published RR = 0.69 (95% CI: 0.55–0.87). Nevertheless, the main focus should be on the authors SEND trial and D’Cruz et al. 2015, as they were the most contemporary and highest quality.
Citation
Hutchison IL, Ridout F, Cheung SMY, Shah N, Hardee P, Surwald C, Thiruchelvam J, Cheng L, Mellor TK, Brennan PA, Baldwin AJ, Shaw RJ, Halfpenny W, Danford M, Whitley S, Smith G, Bailey MW, Woodwards B, Patel M, McManners J, Chan CH, Burns A, Praveen P, Camilleri AC, Avery C, Putnam G, Jones K, Webster K, Smith WP, Edge C, McVicar I, Grew N, Hislop S, Kalavrezos N, Martin IC, Hackshaw A. Correction to: Nationwide randomised trial evaluating elective neck dissection for early stage oral cancer (SEND study) with meta-analysis and concurrent real-world cohort. Br J Cancer. 2021 Dec 23. doi: 10.1038/s41416-021-01678-2. Epub ahead of print. Erratum for: Br J Cancer. 2019 Nov;121(10):827-836. PMID: 34949789.