02- Division 2 Emergency and Medical Services Division
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Advances of cancer genomics in oncology care.
(Clinical Oncology, Elsevier, 2021-12-02)No abstract available. -
Corrigendum to 'An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs'
(Journal of Hepatology, Elsevier, 2021-12-09)No abstract available. -
An international genome-wide meta-analysis of primary biliary cholangitis: novel risk loci and candidate drugs.
(Journal of Hepatology, Elsevier, 2021-09-01)Backgrounds & aims: Primary biliary cholangitis (PBC) is a chronic liver disease in which autoimmune destruction of the small intrahepatic bile ducts eventually leads to cirrhosis. Many patients have inadequate response ... -
Guidance for the implementation of a safety checklist for gastrointestinal endoscopic procedures: European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastroenterology and Endoscopy Nurses and Associates (ESGENA) Position Statement
(Endoscopy, Thieme Verlag KG, 2021-12-14)This Guideline is an official statement of the European Society of Gastrointestinal Endoscopy (ESGE). It provides guidance on the collection and handling of tissue samples during endoscopy of the lower gastrointestinal ... -
Re: Clinical evaluation of a deep-learning-based computer-aided detection system for the detection of pulmonary nodules in a large teaching hospital
(Clinical Radiology, Elsevier, 2022-02-01)No abstract available. -
COVID-19: effect on gastroenterology and hepatology service provision and training: lessons learnt and planning for the future
(World Journal of Gastroenterology, Baishideng Publishing Group Inc., 2021-11-28)In late 2019, reports arose of a new respiratory disease in China, identified as a novel coronavirus, severe acute respiratory syndrome coronavirus 2. The World Health Organisation named the disease caused by the virus ... -
Acute exacerbation of COPD: clinical perspectives and literature review.
(WAJM: West African Journal of Medicine, West African College of Physicians, 2021-10-30)Chronic Obstructive Pulmonary Disease (COPD) COPD is a significant cause of morbidity and the third leading cause of death worldwide. COPD is a chronic progressive disease which may be interspersed by periods of acute ... -
Intramedullary spinal cord metastasis as initial presentation of malignant melanoma: a unique case report and role of contrast vs non-contrast MRI in its diagnosis.
(Cureus, Cureus, 2021-11-18)Intramedullary spinal cord metastasis (ISCM) is a diagnostically challenging and dreadful complication of cancer. Twenty-seven cases of ISCM exclusively related to malignant melanoma have been reported so far in a recent ... -
A review of Mohs micrographic surgery for skin cancer: Part 1 - melanoma and rare skin cancers.
(Clinical and Experimental Dermatology, Wiley, 2021-12-23)Mohs micrographic surgery is a precise and effective method commonly used to treat high risk basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) on the head and neck. Whilst the majority of evidence for Mohs relates ... -
Impaired neutralisation of SARS-CoV-2 delta variant in vaccinated patients with B cell chronic lymphocytic leukaemia.
(Journal of Hematology & Oncology, Springer Nature, 2022-01-09)Background: Immune suppression is a clinical feature of chronic lymphocytic leukaemia (CLL), and patients show increased vulnerability to SARS-CoV-2 infection and suboptimal antibody responses. Method: We studied antibody ... -
Correction to: Nationwide randomised trial evaluating elective neck dissection for early stage oral cancer (SEND study) with meta-analysis and concurrent real-world cohort
(British Journal of Cancer, Springer Nature, 2021-11-23)The original version of this article unfortunately contained a mistake. A correction is needed for one of the trials in the meta-analysis (Fig. 3). For Fakih et al. 1989, the relative risk of death (used as an estimate of ... -
Nationwide randomised trial evaluating elective neck dissection for early stage oral cancer (SEND study) with meta-analysis and concurrent real-world cohort.
(British Journal of Cancer, Springer Nature, 2019-10-15)Background: Guidelines remain unclear over whether patients with early stage oral cancer without overt neck disease benefit from upfront elective neck dissection (END), particularly those with the smallest tumours. Methods: ... -
Inflammatory bowel disease clinical service recovery during the COVID-19 pandemic.
(Frontline Gastroenterology, BMJ Publishing Group, 2022-01-01)The risk of patients with IBD acquiring SARS-CoV-2 and developing COVID-19 will depend on their inherent personal risk factors and modifiable factors such as active IBD and immunosuppression. Fortunately, we will be able ... -
What next for gastroenterology and hepatology trainee networks? Lessons from our surgical colleagues.
(Frontline Gastroenterology, BMJ Publishing Group, 2022-01-01)For once, the COVID-19 pandemic gives us a glimmer of hope. Through the pandemic, we used existing gastroenterology trainee research networks to encourage trainees to collate outcomes from their patients with inflammatory ... -
Bowel cancer screening workforce survey: developing the endoscopy workforce for 2025 and beyond.
(Frontline Gastroenterology, BMJ Publishing Group, 2022-02-23)Aim: The demand for bowel cancer screening (BCS) is expected to increase significantly within the next decade. Little is known about the intentions of the workforce required to meet this demand. The Joint Advisory Group ... -
Daratumumab plus lenalidomide and dexamethasone in transplant-ineligible newly diagnosed multiple myeloma: frailty subgroup analysis of MAIA.
(Leukemia, Springer Nature, 2022-01-02)In the phase 3 MAIA study of patients with transplant-ineligible newly diagnosed multiple myeloma (NDMM), daratumumab plus lenalidomide/dexamethasone (D-Rd) improved progression-free survival (PFS) versus lenalidomide/de ... -
A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study.
(The Lancet Oncology, Elsevier, 2021-11-01)Background: Lynch syndrome is a rare familial cancer syndrome caused by pathogenic variants in the mismatch repair genes MLH1, MSH2, MSH6, or PMS2, that cause predisposition to various cancers, predominantly colorectal and ... -
Daratumumab, lenalidomide, and dexamethasone versus lenalidomide and dexamethasone alone in newly diagnosed multiple myeloma (MAIA): overall survival results from a randomised, open-label, phase 3 trial.
(The Lancet Oncology, Elsevier, 2021-11-01)Background: In the primary analysis of the phase 3 MAIA trial (median follow-up 28·0 months), a significant improvement in progression-free survival was observed with daratumumab plus lenalidomide and dexamethasone versus ... -
Nocturnal seizure monitoring service evaluation of neuro event labs seizure monitoring service ‘NELLI’ in an intellectual disabilities and neurology service.
(The Royal Wolverhampton NHS Trust., 2021-09-23)Nocturnal seizures can be difficult to identify, characterise and quantify. The gold standard for evaluating seizures is video EEG (vEEG). Long waiting times can hamper follow up care whilst equipment toleration and ... -
“Do patients’ pre-pandemic clinic experiences influence their preference for remote consultations?”
(The Royal Wolverhampton NHS Trust., 2021-09-23)In light of the COVID-19 pandemic, outpatient services have been restructured to facilitate remote consultations. As the pandemic has entered second and third ‘waves’, considering patients’ perspectives regarding remote ...
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