2- Division 2 Emergency and Medical Services Division
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Resuming endoscopy during COVID-19 pandemic: ESGE, WEO and WGO Joint Cascade Guideline for Resource Limited Settings.
(Endoscopy International Open, Thieme Verlag KG, 2021-04-01)The ongoing COVID-19 pandemic has forced endoscopy units to stop or markedly reduce all elective endoscopic procedures and has consequently contracted endoscopic capacity throughout the world, with growing concern for a ... -
Impact of COVID-19 on gynaecological oncology; a global perspective.
(Heliyon, Elsevier, 2021-04-01)The coronavirus pandemic caused global devastation with over 2 million deaths and put unprecedented pressure on health care facilities world-wide. The response to the pandemic differed globally as countries faced different ... -
Letter: impact of Epstein-Barr virus serological status on clinical outcomes in adult patients with inflammatory bowel disease.
(Alimentary Pharmacology & Therapeutics, Wiley, 2019-02-01)No abstract available. -
Potential clinical error arising from use of HbA1c in diabetes: effects of the gycation gap.
(Endocrine Reviews, Oxford University Press, 2019-08-01)The glycation gap (GGap) and the similar hemoglobin glycation index (HGI) define consistent differences between glycated hemoglobin and actual glycemia derived from fructosamine or mean blood glucose, respectively. Such a ... -
Paediatric minor facial trauma resulting in invasive group A streptococcal orofacial infections: two case reports.
(Oral Surgery, Wiley, 2019-03-11)Invasive Group A Streptococcus infections can be underestimated and develop rapidly into serious necrotising soft tissue infections associated with significant morbidity and mortality. We report two children who presented ... -
The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide, or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial.
(The Lancet, 2021-04-10)Background Levetiracetam and zonisamide are licensed as monotherapy for patients with focal epilepsy, but there is uncertainty as to whether they should be recommended as first-line treatments because of insufficient ... -
The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial
(The Lancet, Elsevier, 2010-11-01)Background Valproate is a first-line treatment for patients with newly diagnosed idiopathic generalised or difficult to classify epilepsy, but not for women of child-bearing potential because of teratogenicity. Levetiracetam ... -
Pitfalls in cerebrospinal fluid spectroscopy results for the diagnosis of subarachnoid haemorrhage.
(British Journal of Neurosurgery, Taylor & Group, 2010-12-01)No abstract available. -
Community based epilepsy care: putting patients at the heart of management.
(Brainworks, Brainwork, 2019-01-01)Phil discusses his award-winning community-based epilepsy service and asked his advice for other clinicians seeking to move to this model of care. -
Transforming care.
(Epilepsy Professional, Epilepsy Organisation, 2013-06)Community-based epilepsy services can provide expert, safe, local care to people with the condition. Partnership between the patient, their family and carers, nurse, secondary care neurology and primary care is vital. ... -
Can teaching simple relaxation techniques to people with epilepsy improve their seizure, frequency and quality of life?
(Epilepsy Care, 2007)On a smaller scale, the study has shown that a focus on anxiety management can be helpful when managing the care of people with refractory epilepsy. Clinicians within the Department of Neurology are increasingly aware of ... -
Penetration of the heart by an airgun pellet: a case without significant effusion or valvular injury.
(Annals of Thoracic Surgery, Elsevier, 2019-07-01)Cardiac gunshot injuries are rare in the United Kingdom, but they are associated with significant morbidity and mortality. We present the case of a young male who was shot at close range with a low-caliber air rifle. The ... -
Safety and efficacy of eslicarbazepine acetate (zebinix) in everyday clinical practice using a retrospective multicentre audit.
(Journal of Neurology, Neurosurgery and Psychiatry, BMJ Publishing Group, 2014-09-09)Purpose We report on the safety and efficacy of eslicarbazepine acetate (ESL) in routine clinical practice. Method Retrospective multicentre audit of outcomes following ESL treatment for localisation-related epilepsy ... -
Impact of the coronavirus infectious disease (COVID-19) pandemic on the provision of inflammatory bowel disease (IBD) antenatal care and outcomes of pregnancies in women with IBD.
(BMJ Open Gastroenterology, BMJ Publishing Group, 2021-03-22)Background: The impact of COVID-19 on pregnant inflammatory bowel disease (IBD) patients is currently unknown. Reconfiguration of services during the pandemic may negatively affect medical and obstetric care. We aimed to ... -
EXPRESS: Analytical method comparisons do not consider the comparison of reference ranges which may lead to differences in diagnosis and patient management: a case for clinical discordance checks.
(Annals of Clinical Biochemistry, Sage Journals, 2021-03-31)Analytical method comparisons do not consider the comparison of reference ranges which may lead to differences in diagnosis and patient management: A case for clinical discordance checks. -
Oral and Intravenous iron therapy differentially alter the on- and off-tumor microbiota in anemic colorectal cancer patients.
(Cancers, MDPI, 2021-03-16)Iron deficiency anemia is a common complication of colorectal cancer and may require iron therapy. Oral iron can increase the iron available to gut bacteria and may alter the colonic microbiota. We performed an intervention ... -
Phase I trial of the MEK inhibitor selumetinib in combination with thoracic radiotherapy in non-small cell lung cancer.
(Clinical and Translational Radiation Oncology, Elsevier, 2021-02-25)Background: The RAS/RAF/MEK/ERK signalling pathway has a pivotal role in cancer proliferation and modulating treatment response. Selumetinib inhibits MEK and enhances effects of radiotherapy in preclinical studies. Patients ... -
Triplegic stroke following air embolism from bronchogenic cyst secondary to barotrauma.
(Annals of Thoracic Surgery, Elsevier, 2021-03-20)Emergency medical assistance is rare when concerning air travel. Pulmonary barotrauma during air travel can occur in asymptomatic patients who have underlying intra-parenchymal pulmonary pathology such as bullae or ... -
Persistently abnormal thyroid function tests and palpitations.
(CPD Clinical Biochemistry, Rila Publishing Ltd, 2012-10-01)No abstract available. -
Weight loss and hyponatraemia.
(British Medical Journal, BMJ Publishing Group Ltd, 2011-03-02)No abstract available.