2021 Publications
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The mutual benefits of patient and public involvement in research: an example from a feasibility study (MoTaStim-Foot).
(Research Involvement and Engagement, Springer Nature, 2021-12-04)Background: Patient and public involvement (PPI) in research has increased steadily over the last two decades and is now both expected and appropriately resourced by many funding bodies, including the National Institute ... -
Is there a role for natural desiccated thyroid in the treatment of levothyroxine unresponsive hypothyroidism? Results from a consecutive case series.
(International Journal of Clinical Practice, Wiley Online Library, 2021-11-20)Introduction: Some levothyroxine unresponsive individuals with hypothyroidism are prescribed a natural desiccated thyroid (NDT) preparation such as Armour Thyroid® or ERFA Thyroid®. These contain a mixture of levothyroxine ... -
Diagnostic yield of rare skeletal dysplasia conditions in the radiogenomics era.
(BMC Medical Genomics, Springer Nature, 2021-06-06)Background: Skeletal dysplasia (SD) conditions are rare genetic diseases of the skeleton, encompassing a heterogeneous group of over 400 disorders, and represent approximately 5% of all congenital anomalies. Developments ... -
COVID-19 multidisciplinary working group.
(Clinical Medicine Journal, Royal College of Physicians, 2021-07-01)No abstract available. -
Insight from patient and healthcare professionals on the implementation of virtual clinics patients with inflammatory bowel disease
(Frontline Gastroenterology, BMJ Journals, 2021-02-25)Introduction: During COVID-19, the management of outpatient inflammatory bowel disease (IBD) changed from face-to-face (F2F) to telephone and video consultations across the UK. We surveyed patients with IBD and IBD healthcare ... -
Pharmacokinetics and pharmacodynamics of oral P2Y12 inhibitors during the acute phase of a myocardial infarction: a systematic review.
(Thrombosis Research, Elsevier, 2016-07-01)Background: The immediate administration of oral antiplatelet therapy in the form of aspirin plus a P2Y12 inhibitor is the universally recognised standard of care for patients who present with acute myocardial infarction. ... -
Menopausal status, age and management among women living with HIV in the UK.
(HIV Medicine, Wiley Online, 2021-10-01)Background There is currently little evidence exploring menopausal status, age at last menstrual period (LMP) and management of menopause among women living with HIV aged 45–60 years in England. Methods Socio-demographic, ... -
Harnessing the true power of altmetrics to track engagement.
(Journal of Korean Medical Science, 2021-12-13)Altmetrics has recently been at the forefront of tracking medical literature propagation on social media in the modern era. With the rapidly evolving landscape of social media for academia, there's room to revise the ... -
Low sex hormone binding globulin: a potential predictor of future glucose dysregulation in women.
(Cardiovascular Endocrinology & Metabolism, Wolters Kluwer, 2021-07-29)Sex hormone binding globulin (SHBG) concentration associates with insulin-resistance. We looked at the relation between baseline SHBG concentration and future glycaemic status over an up to 10-year period, for women who ... -
The risk factors potentially influencing risk of serious illness/death in people with diabetes, following SARS-CoV-2 infection: what needs to be done from here.
(Cardiovascular Endocrinology & Metabolism, Wolters Kluwer, 2021-10-28)In conclusion, as the COVID-19 pandemic moves into a new phase in Europe and some other parts of the world, much remains to be determined about why having diabetes increases the risk of serious consequences of a COVID-19 ... -
Incidence and risk factors of long COVID in the UK: a single-centre observational study.
(Journal of the Royal College of Physicians of Edinburgh, Royal College of Physicians of Edinburgh, 2021-12-01)Background: Studies to evaluate long COVID symptoms and their risk factors are limited. We evaluated the presence of long COVID and its risk factors in patients discharged from a hospital with COVID-19 illness. Methods: ... -
Corrigendum to 'An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs'
(Journal of Hepatology, Elsevier, 2021-12-09)No abstract available. -
An international genome-wide meta-analysis of primary biliary cholangitis: novel risk loci and candidate drugs.
(Journal of Hepatology, Elsevier, 2021-09-01)Backgrounds & aims: Primary biliary cholangitis (PBC) is a chronic liver disease in which autoimmune destruction of the small intrahepatic bile ducts eventually leads to cirrhosis. Many patients have inadequate response ... -
COVID-19: effect on gastroenterology and hepatology service provision and training: lessons learnt and planning for the future
(World Journal of Gastroenterology, Baishideng Publishing Group Inc., 2021-11-28)In late 2019, reports arose of a new respiratory disease in China, identified as a novel coronavirus, severe acute respiratory syndrome coronavirus 2. The World Health Organisation named the disease caused by the virus ... -
Do immediately placed implants have better outcomes when placed with a minimal split-thickness envelope flap?
(Evidence-Based Dentistry, Springer Nature, 2021-12-16)Design Randomised, controlled, single-blind, single-centre clinical trial. Case selection Adult patients in need of a single tooth extraction in the anterior maxillary and premolar region. Full mouth plaque scores below ... -
Acute exacerbation of COPD: clinical perspectives and literature review.
(WAJM: West African Journal of Medicine, West African College of Physicians, 2021-10-30)Chronic Obstructive Pulmonary Disease (COPD) COPD is a significant cause of morbidity and the third leading cause of death worldwide. COPD is a chronic progressive disease which may be interspersed by periods of acute ... -
Intramedullary spinal cord metastasis as initial presentation of malignant melanoma: a unique case report and role of contrast vs non-contrast MRI in its diagnosis.
(Cureus, Cureus, 2021-11-18)Intramedullary spinal cord metastasis (ISCM) is a diagnostically challenging and dreadful complication of cancer. Twenty-seven cases of ISCM exclusively related to malignant melanoma have been reported so far in a recent ... -
Correction to: Nationwide randomised trial evaluating elective neck dissection for early stage oral cancer (SEND study) with meta-analysis and concurrent real-world cohort
(British Journal of Cancer, Springer Nature, 2021-11-23)The original version of this article unfortunately contained a mistake. A correction is needed for one of the trials in the meta-analysis (Fig. 3). For Fakih et al. 1989, the relative risk of death (used as an estimate of ... -
COVID-19 and critical care capacity: can we mitigate demand?
(Respirology, Wiley, 2021-12-05)No abstract available. -
Long COVID from rheumatology perspective - a narrative review.
(Clinical Rheumatology, Springer Nature, 2021-10-30)Long-term sequel of acute COVID-19, commonly referred to as long COVID, has affected millions of patients worldwide. Long COVID patients display persistent or relapsing and remitting symptoms that include fatigue, ...