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Reverse myocardial remodeling following valve repair in patients with chronic severe primary degenerative mitral regurgitation.
(JACC: Cardiovascular Imaging, Elsevier, 2021-08-11)Objectives: The aims of this study were to quantify preoperative myocardial fibrosis using late gadolinium enhancement (LGE), extracellular volume fraction (ECV%), and indexed extracellular volume (iECV) on cardiac magnetic ... -
Balanced forced-diuresis compared to control as a reno-protective approach in cardiac surgery: secondary outcome of a randomized controlled trial, assessment of neutrophil gelatinase-associated lipocalin levels.
(World Journal of Otorhinolaryngology - Head and Neck Surgery, Springer Nature, 2021-08-24)Background: Neutrophil gelatinase-associated lipocalin (NGAL) is a recognised biomarker for acute kidney injury (AKI).This study investigated the impact of balanced forced-diuresis using RenalGuard® system (RG), in reducing ... -
Implementation of an acute tonsillitis management protocol within a clinical decisions unit.
(Annals of The Royal College of Surgeons of England, The Royal College of Surgeons of England, 2021-08-26)Introduction: With tonsillectomy surgery subject to increasingly strict commissioning criteria over the past 20 years in the UK, the total number of admissions for acute tonsillitis has been rising steadily. Multiple ... -
Ethnicity and breast cancer in the UK: Where are we now?
(European Journal of Surgical Oncology, Elsevier, 2021-08-24)Outcomes from breast cancer for women in the UK have improved significantly over recent decades. These gains are largely attributable to a combination of earlier diagnosis and access to treatments delivered to patients by ... -
The evolution of sinus surgery in England in the last decade - an observational study.
(World Journal of Otorhinolaryngology - Head and Neck Surgery, Chinese Medical Association., 2021-07-01)Background and objective: Sinus surgery has seen significant changes over the years with advancements in instruments, endoscopes and imaging. This study aimed to use Hospital Episode Statistics (HES) data to review the ... -
Fingolimod: therapeutic mechanisms and ocular adverse effects.
(Eye (London), Nature Publishing Group, 2017-02-01)Fingolimod is an oral immunomodulating drug used in the management of relapsing-remitting multiple sclerosis (RRMS). We aim to review the published literature on ocular manifestations of fingolimod therapy and their possible ... -
Positioning of the anaesthetised patient during robotically assisted laparoscopic surgery: perioperative staff experiences.
(Journal of Perioperative Practice, SAGE Publications, 2016-03-01)Safe, patient centred care is a large part of our trust values at the Royal Wolverhampton NHS Trust. Robotic assisted laparoscopic surgery (RALS) is still in its infancy within our trust, and we decided to look at what we ... -
Infection prevention in breast implant surgery - a review of the surgical evidence, guidelines and a checklist.
(European Journal of Surgical Oncology, Elsevier, 2016-08-01)No abstract available. -
Case series investigating the efficacy and safety of bilateral fluocinolone acetonide (ILUVIEN(®)) in patients with diabetic macular edema: 10 eyes with 12 months follow-up.
(Ophthalmology and Therapy, Springer Nature, 2016-06-01)Introduction: This short case series presents the results from 5 patients with bilateral chronic diabetic macular edema (DME), 12 months after they were initially treated with ILUVIEN (®) [0.2 μg/day fluocinolone acetonide ... -
Case series investigating the efficacy and safety of bilateral fluocinolone acetonide (ILUVIEN(®)) in patients with diabetic macular edema.
(Ophthalmology and Therapy, Springer Nature, 2016-06-01)Introduction: Patients with diabetic macular edema (DME), a chronic, vision-limiting condition, may be insufficiently responsive to standard-of-care anti-vascular endothelial growth factor (VEGF) and/or laser therapies. ... -
Repeatability of swept-source optical coherence tomography retinal and choroidal thickness measurements in neovascular age-related macular degeneration.
(British Journal of Ophthalmology, BMJ Publishing Group, 2017-05-01)Background: The aim was to determine the intrasession repeatability of swept-source optical coherence tomography (SS-OCT)-derived retinal and choroidal thickness measurements in eyes with neovascular age-related macular ... -
Provision of acute medicine services for pregnant women in UK hospitals: Data from the Society for Acute Medicine Benchmarking Audit 2019.
(Obstetric Medicine, Sage Journals, 2021-06-01)Background: Medical problems during pregnancy are the leading cause of maternal mortality in the UK. Pregnant women often present through acute services to the medical team, requiring timely access to appropriate services, ... -
Utility of global longitudinal strain to detect significant coronary artery disease, its extent and severity in patients with stable ischemic heart disease.
(Echocardiography, Wiley, 2020-12-01)Background: Early changes in cardiac function due to ischemia may be detected by global longitudinal peak systolic strain (GLS). Till date, no Indian data exist regarding role of GLS in stable ischemic heart disease (SIHD) ... -
Utility of non-invasive cardiac imaging assessment in coronavirus disease 2019.
(Frontiers in Cardiovascular Medicine, Frontiers Media, 2021-05-21)Coronavirus disease 2019 (COVID-19) was initially regarded as a disease of the lungs, which manifests as an acute respiratory illness and pneumonia, although more recently cardiac complications have been well-characterised. ... -
Acute coronary syndrome with separate right sinus origin of all three coronary arteries: diagnosis and successful left anterior descending percutaneous coronary intervention.
(European Heart Journal - Case Reports, Oxford University Press, 2021-03-31)No abstract available. -
Intravitreal ranibizumab versus aflibercept versus bevacizumab for macular oedema due to central retinal vein occlusion: the LEAVO non-inferiority three-arm RCT.
(Health Technology Assessment, NIHR Journals Library, 2021-06-01)Background: Licensed ranibizumab (0.5 mg/0.05 ml Lucentis®; Novartis International AG, Basel, Switzerland) and aflibercept (2 mg/0.05 ml Eylea®; Bayer AG, Leverkusen, Germany) and unlicensed bevacizumab (1.25 mg/0.05 ml ... -
Antegrade ureteric embolization following transection and ligature in a lateral pelvic wall squamous cell carcinoma: technique and literature review
(Journal of Obstetrics and Gynaecology Research, Wiley Online, 2021-07-16)Iatrogenic injuries to the ureter are a rare event in gynecological surgery. They are often managed via stent insertion or nephrostomies. While embolization is commonly utilized for the sealing of vessels, its uses in ... -
Translating evidence into practice: recommendations by a UK expert panel on the use of aflibercept in diabetic macular oedema.
(Eye, Springer Nature, 2020-05-01)Objectives: This paper describes recommendations from a panel of UK retina experts on aflibercept in diabetic macular oedema (DMO). Methods: A roundtable meeting was held in London, UK in March 2018. The meeting was ... -
Emergency management of neck stoma patients during the coronavirus pandemic: a national nurse survey.
(British Journal of Nursing, Mark Allen Publishing., 2021-06-24)Background: Neck stoma patient care involves significant clinical complexity. Inadequate staff training, equipment provision and infrastructure have all been highlighted as causes for avoidable patient harm. Aims: To ... -
Psychological distress and trauma during the COVID-19 pandemic: survey of doctors practising anaesthesia, intensive care medicine, and emergency medicine in the United Kingdom and Republic of Ireland.
(British Journal of Anaesthesia, Elsevier, 2021-08-01)No abstract available.
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