Ophthalmology Services (Wolverhampton Eye Infirmary)
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Recent Submissions
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Ranibizumab treatment in treatment-naive neovascular age-related macular degeneration: results from LUMINOUS, a Global Real-World Study.
(Retina, Lippincott, Williams & Wilkins., 2021-09-01)Purpose: To evaluate the effectiveness, safety, and treatment patterns of ranibizumab 0.5 mg in treatment-naive patients with neovascular age-related macular degeneration enrolled in LUMINOUS study. Methods: This 5-year, ... -
Risk factors and incidence of macular edema after cataract surgery: a database study of 81984 eyes.
(Ophthalmology, Elsevier, 2016-02-01)Purpose: To define the incidence of pseudophakic macular edema (PME) after cataract surgery and to identify contributory risk factors. Design: Retrospective database study of electronic medical records (EMRs). Participants: ... -
Correction to: Cost effectiveness of ranibizumab vs aflibercept vs bevacizumab for the treatment of macular oedema due to central retinal vein occlusion:the LEAVO study.
(PharmacoEconomics, Springer Nature, 2021-06-19)The article Cost Effectiveness of Ranibizumab vs Aflibercept vs Bevacizumab for the Treatment of Macular Oedema Due to Central Retinal Vein Occlusion: The LEAVO Study,written by Becky Pennington, Abualbishr Alshreef, Laura ... -
Oral medications for central serous chorioretinopathy: a literature review.
(Eye, Springer Nature, 2020-05-01)Central serous chorioretinopathy (CSCR) is characterised by acute or chronic neurosensory detachments of the retina, usually in the posterior pole, with or without associated detachments of retinal pigment epithelium. ... -
Primary eccrine adenocarcinoma: a rare but dangerous lesion of the eyelid.
(Journal of Clinical & Aesthetic Dermatology, Matrix Medical Communications, LLC, 2021-04-01)Sweat gland carcinomas can be of eccrine or apocrine origin, with the former being more common in the eyelid. They can also be of three different types, the most common of which is mucin-producing sweat gland carcinoma, ... -
The clinical relevance of ultra-widefield angiography findings in patients with central retinal vein occlusion and macular oedema receiving anti-VEGF therapy.
(Eye, Springer Nature, 2021-05-25)Aims: To report, using ultra-widefield angiography (UWFA) the area, distribution, and change in retinal capillary nonperfusion (RCNP) at baseline and 100 weeks in eyes with central retinal vein occlusion (CRVO) receiving ... -
Comparison of 1-year surgical outcomes of combined cataract surgery and gonioscopy-assisted transluminal trabeculotomy (GATT) versus cataract surgery and iStent Inject.
(Graefe's Archive for Clinical and Experimental Ophthalmology, Springer Nature, 2021-05-20)Purpose: Evaluate the efficacy, safety, and complication rates of phacoemulsification cataract surgery when combined with either gonioscopy-assisted transluminal trabeculotomy (GATT) or iStent Inject. Methods: This is ... -
Pearl necklace sign in diabetic macular edema: evaluation and significance.
(Indian Journal of Ophthalmology, Medknow Publications, 2016-11-01)Purpose: (1) The purpose of this study was to describe significance and prevalence of the newly reported pearl necklace spectral domain optical coherence tomography (SDOCT) sign, in diabetic macular edema (DMO), (2) to ... -
Vitrectomy for bilateral macular schisis without apparent optic disc anomalies.
(GMS Ophthalmology Cases, German Medical Science, 2016-09-13)A 78-year-old man complained of bilateral visual acuity loss. Optical coherence tomography examination showed bilateral macular schisis with fluid accumulation in the external retinal layers without vitreous traction. ... -
Ophthalmology research in the UK's National Health Service: the structure and performance of the NIHR's Ophthalmology research portfolio.
(Eye (London), Springer Nature, 2019-04-01)Purpose: To report on the composition and performance of the portfolio of Ophthalmology research studies in the United Kingdom's National Institute for Health Research (NIHR) Clinical Research Network (UK CRN). Methods: ... -
Corneal neovascularization: updates on pathophysiology, investigations & management.
(Romanian Journal of Ophthalmology, Romanian Society of Ophthalmology, 2019-02-09)Objective. Corneal neovascularization is a sight-threatening condition affecting more than 1.4 million people per year. Left untreated, it can lead to tissue scarring, oedema, lipid deposition, and persistent inflammation ... -
Cost effectiveness of ranibizumab vs aflibercept vs bevacizumab for the treatment of macular oedema due to central retinal vein occlusion: the LEAVO study.
(PharmacoEconomics, Springer Nature, 2021-04-26)Background: We aimed to assess the cost effectiveness of intravitreal ranibizumab (Lucentis), aflibercept (Eylea) and bevacizumab (Avastin) for the treatment of macular oedema due to central retinal vein occlusion. Methods: ... -
RNA-seq analysis of ageing human retinal pigment epithelium: unexpected up-regulation of visual cycle gene transcription.
(Journal of Cellular and Molecular Medicine, Wiley Online, 2021-06-01)Ageing presents adverse effects on the retina and is the primary risk factor for age-related macular degeneration (AMD). We report the first RNA-seq analysis of age-related transcriptional changes in the human retinal ... -
Ocular radiation exposure during endoscopic retrograde cholangiopancreatography: a meta-analysis of studies.
(European Journal of Gastroenterology & Hepatology, Wolters Kluwer, 2019-04-01)Background: The increasing complexity involved in procedures requiring fluoroscopy such as endoscopic retrograde cholangiopancreatography (ERCP) results in heightened screening times with attendant radiation exposure during ... -
Importance of anatomical efficacy for disease control in neovascular AMD: an expert opinion.
(Ophthalmology and Therapy, Springer Nature, 2021-06-01)Background: Neovascular age-related macular degeneration (nAMD) presents a significant treatment burden for patients, carers and medical retina services. However, significant debate remains regarding how best to manage ... -
Migration of the XEN45 gel stent into the anterior chamber managed by trimming the implant.
(Journal of Glaucoma, Wolters Kluwer, 2021-04-02)We report a case of migration of the XEN45 gel stent into the anterior chamber successfully treated with trimming of the implant. To the best of our knowledge this management strategy for migration of the implant has not ... -
Allogenic dehydrated human pericardium patch graft (Tutoplast): A novel use for reconstruction in orbital implant exposure.
(European Journal of Ophthalmology, Sage Journals, 2021-03-18)Purpose: Exposure of orbital implant post enucleation or evisceration remains one of the common complications irrespective of the type of implant used. Dermis fat graft and temporalis fascia have been used to repair the ... -
Retinal vein occlusion as the presenting feature of Cushing's syndrome.
(BMJ Case Reports, BMJ Journals, 2021-01-25)A 53-year-old man presented to his optician with blurring of vision in the right eye and was diagnosed to have branch retinal vein occlusion. Over the following 3 months, he had further progressive visual impairment due ... -
Intraocular pressure reduction after real-world cataract surgery
(Journal of Glaucoma, Wolters Kluwer, 2020-08-01)A large cohort undergoing cataract extraction was retrospectively analyzed to ascertain the degree of real-world intraocular pressure (IOP) reduction in normal eyes and those with glaucoma, and a predictive formula was ... -
Intraoperative complications and visual outcomes of cataract surgery in diabetes mellitus: a multicenter database study.
(American Journal of Ophthalmology, Elsevier., 2021-05-01)Purpose: To compare the visual outcome and the rate of intraoperative complications in eyes of diabetic and non-diabetic patients undergoing phacoemulsification over 15 years DESIGN: Retrospective clinical cohort study ...
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