Browsing Gastroenterology and Hepatology Services by Issue Date
Now showing items 1-20 of 176
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Shortness of breath: flushing out the diagnosis.
(Annals of Clinical Biochemistry, Sage Journals, 2010-03-01)We report a 63-year-old man who presented with breathlessness and weight loss and was diagnosed on echocardiography to have carcinoid heart disease. It was later transpired that he underwent surgical removal of an ileal ... -
Gastropericardial fistula: a potential role for conservative treatment.
(European Journal of Gastroenterology & Hepatology, Wolters Kluwer., 2012-11-01)Gastropericardial fistulae are rare entities associated with considerable mortality and morbidity. Most commonly seen secondary to surgery and trauma, they also occur because of peptic ulcer disease. Surgical correction ... -
Between-assay variability of faecal calprotectin enzyme-linked immunosorbent assay kits.
(Annals of Clinical Biochemistry, Sage Journals, 2013-01-01)Background: Faecal calprotectin (f-Cp), a marker of intestinal inflammation, can be used to distinguish between functional and organic bowel disease. F-Cp, following extraction, is commonly quantified using enzyme-linked ... -
#FGCUP2023 - and the review paper of the year goes to…
(Frontline Gastroenterology, BMJ Publishing Group., 2013-03-15)Awards season is on us and none is more important than the #FGCUP2023 readers’ choice award. Now in its second year (and soon becoming a permanent annual fixture), the #FGCUP2023 allows readers across the world to vote for ... -
Emergency endoscopic retrograde cholangiopancreatography in critically ill patients is a safe and effective procedure.
(Frontline Gastroenterology, BMJ Journals, 2013-04-01)Emergency ERCP may be required in patients with severe cholangitis who rapidly deteriorate with multi-organ dysfunction and who cannot wait until the next available elective list. A significant proportion of patients require ... -
Do differences in female sex hormone levels contribute to gastro-oesophageal reflux disease?
(European Journal of Gastroenterology and Hepatology, Wolters Kluwer., 2013-07-01)Background Hormone replacement therapy is associated with both reflux symptoms and oesophagitis. During pregnancy, elevated sex hormones are thought to contribute to the high prevalence of reflux symptoms. Increased ... -
Who should be treating rectal cancer in 2013?
(British Journal of Hospital Medicine, MAG Online Library, 2013-07-01)Management of rectal cancer has advanced significantly over the last 30 years. As the complexity of treatment increases the question of superspecialization has arisen as a means of concentrating expertise and improving ... -
Management of the malignant colorectal polyp: ACPGBI position statement.
(Colorectal Disease, Blackwell Science Ltd, 2013-08-15)A colorectal polyp is an abnormal protrusion of the mucosa into the bowel lumen that is classified by histopathological examination (Fig. 1). Adenomas are a common finding during colonoscopy in symptomatic patients and in ... -
Removal of an embedded "covered" biliary stent by the "stent-in-stent" technique.
(World Journal of Gastroenterology, Baishideng Publishing Group., 2013-09-28)A 46-year-old man was admitted with obstructive jaundice and cross-sectional imaging with computed tomography suggested distal biliary obstruction. A distal common bile duct stricture was found at endoscopic retrograde ... -
A novel method for determining the difficulty of colonoscopic polypectomy.
(Frontline Gastroenterology, BMJ Journals., 2013-10-01)Introduction: Endoscopists are now expected to perform polypectomy routinely. Colonic polypectomy varies in difficulty, depending on polyp morphology, size, location and access. The measurement of the degree of difficulty ... -
Everolimus for previously treated advanced gastric cancer: results of the randomized, double-blind, phase III GRANITE-1 study.
(Journal of Clinical Oncology, American Social of Clinical Oncology, 2013-11-01)Purpose The oral mammalian target of rapamycin inhibitor everolimus demonstrated promising efficacy in a phase II study of pretreated advanced gastric cancer. This international, double-blind, phase III study compared ... -
The role of near-patient coeliac serology testing in the follow-up of patients with coeliac disease.
(BMJ Journals, BMJ Journals, 2014-01-01)Objective This pilot study was undertaken to assess the validity and effectiveness of near-patient coeliac immunological testing, compared to standard laboratory immunological techniques, used in the context of dietician-led ... -
ERCP in cholangitis.
(Gastrointestinal Endoscopy, Elsevier., 2014-02-01)Navaneethan et al1 present elegant data examining the variables associated with 30-day readmission in patients undergoing ERCP for cholangitis. However, the methodology used for their statistical analysis deserves critique ... -
Metachronous colorectal cancer: a competing risks analysis with consideration for a stratified approach to surveillance colonoscopy.
(Journal of Surgical Oncology, Wiley Online, 2014-04-01)Background The incidence of metachronous cancer will become an important clinical consideration as the life expectancy of the population increases and as rates of curative resection improve. Objective To assess the ... -
Is there any value in measuring faecal calprotectin in Clostridium difficile positive faecal samples?
(Journal of Medical Microbiology, Microbiology Society, 2014-04-01)Markers of intestinal inflammation have been proposed for inclusion in Clostridium difficile diagnostic algorithms. Faecal calprotectin (f-Cp), a sensitive marker of intestinal inflammation, was evaluated for utility in ... -
How commonly is upper gastrointestinal cancer missed at endoscopy? A meta-analysis.
(European International Open, Thieme Verlag KG, 2014-06-01)Background and study aims: Upper gastrointestinal (UGI) cancer in the Western world usually presents at an advanced stage, when opportunities for curative therapy are limited. The failure to detect subtle, early-stage UGI ... -
Guidance on the management of diarrhoea during cancer chemotherapy.
(The Lancet Oncology., Elsevier., 2014-09-15)Diarrhoea induced by chemotherapy in cancer patients is common, causes notable morbidity and mortality, and is managed inconsistently. Previous management guidelines were based on poor evidence and neglect physiological ... -
Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial
(The Lancet, Elsevier., 2014-10-01)Background VEGFR-2 has a role in gastric cancer pathogenesis and progression. We assessed whether ramucirumab, a monoclonal antibody VEGFR-2 antagonist, in combination with paclitaxel would increase overall survival in ... -
Is hormone replacement therapy in post-menopausal women associated with a reduced risk of oesophageal cancer?
(United European Gastroenterology Journal, Wiley Online, 2014-10-01)Purpose The rise in oesophageal adenocarcinoma incidence in women with age is delayed compared with men until the post-menopausal period. A matched cohort study was therefore undertaken of post-menopausal women on hormone ... -
A rare case of jejuno-ileal intussusception secondary to a gastrointestinal stromal tumour.
(Journal of Surgical Case Reports, Oxford University Press, 2015-01-08)Gastrointestinal stromal tumours (GISTs) are rare tumours, making up 0.2–1% of gastrointestinal malignancies [Zakaria and Daradkeh (Jejunojejunal intussusception induced by a gastrointestinal stromal tumour. Case Rep Surg ...