Pulmonary sarcoidosis: diagnostic and treatment update.
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Authors
Mann, Jonathan
Fahim, Ahmed
Issue Date
2014-05-16
Journal
Type
Peer-Reviewed Publication
Review
Review
Keywords
Corticosteroids
Granulomatous inflammation
Immunosuppression
Sarcoidosis
Arenal cortex hormones
Anti-inflammatory agents
Pulmonary sarcoidosis
Immunosuppressive agents
Diagnosis
Treatment
Granulomatous inflammation
Immunosuppression
Sarcoidosis
Arenal cortex hormones
Anti-inflammatory agents
Pulmonary sarcoidosis
Immunosuppressive agents
Diagnosis
Treatment
Journal Title
Expert Review of Respiratory Medicine.
Volume
8
Issue
4
Begin page
493
End page
501
Abstract
Sarcoidosis is a multisystem disorder of uncertain etiology, characterized by non-caseating granuloma formation in the affected organs. Significant progress has been made in the understanding of the immunopathological aspects of this disease over recent years. However, the causative agent(s) remain unknown. There remains controversy around the best treatment regimens and duration of immunosuppressive therapy. This is largely related to the heterogeneity of disease, a paucity of large randomized controlled trials and the fact that a significant proportion of patients do not require treatment. This review aims to summarize the evidence for the management of pulmonary sarcoidosis and to provide an update on recent developments in diagnosis and treatment.
Citation
Fahim A, Mann JS. Pulmonary sarcoidosis: diagnostic and treatment update. Expert Rev Respir Med. 2014 Aug;8(4):493-501. doi: 10.1586/17476348.2014.919225. Epub 2014 May 16. PMID: 24832794.