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Who should be treating rectal cancer in 2013?
(British Journal of Hospital Medicine, MAG Online Library, 2013-07-01)Management of rectal cancer has advanced significantly over the last 30 years. As the complexity of treatment increases the question of superspecialization has arisen as a means of concentrating expertise and improving ... -
Introduction of the professional nurse advocate role using a quality implementation framework.
(British Journal of Nursing, Mark Allen Group., 2023-04-20)Background: Implementation of the professional nurse advocate (PNA) role and the Advocating and Educating for QUality ImProvement model (A-EQUIP) in nursing is relatively new. The model aims to build personal and professional ... -
Vitamin B group levels and supplementations in dermatology.
(Dermatology Reports, PagePress, 2023-03-07)Irregularities of vitamin levels are being increasingly identified associated with skin conditions, and systemic and topical therapies have shown promising improvements. There have been some remarkable improvements achieved, ... -
#FGCUP2023 - and the review paper of the year goes to…
(Frontline Gastroenterology, BMJ Publishing Group., 2013-03-15)Awards season is on us and none is more important than the #FGCUP2023 readers’ choice award. Now in its second year (and soon becoming a permanent annual fixture), the #FGCUP2023 allows readers across the world to vote for ... -
JAG consensus statements for training and certification in flexible sigmoidoscopy.
(Frontline Gastroenterology, BMJ journals., 2023-01-27)Introduction: Joint Advisory Group (JAG) certification in endoscopy is awarded when trainees attain minimum competency standards for independent practice. A national evidence-based review was undertaken to update standards ... -
JAG consensus statements for training and certification in colonoscopy.
(Frontline Gastroenterology, BMJ Journals., 2023-01-27)Introduction: In the UK, endoscopy certification is awarded when trainees attain minimum competency standards for independent practice. A national evidence-based review was undertaken to update and develop standards and ... -
Efficacy and safety of brolucizumab versus aflibercept in eyes with early persistent retinal fluid: 96-week outcomes from the HAWK and HARRIER studies.
(Eye, Springer Nature, 2023-04-01)Objective: Post-hoc analysis to compare the outcomes of brolucizumab 6 mg vs. aflibercept 2 mg in neovascular age-related macular degeneration (nAMD) patients with early persistent retinal fluid in HAWK and HARRIER. Methods: ... -
The use and efficacy of FFR-CT: real-world multicenter audit of clinical data with cost analysis.
(1936-878X, Elsevier, 2023-03-09)Background: Fractional flow reserve-computed tomography (FFR-CT) is endorsed by UK and U.S. chest pain guidelines, but its clinical effectiveness and cost benefit in real-world practice are unknown. Objectives: To audit ... -
Clinico-pathologic relationships with Ki67 and its change with short-term aromatase inhibitor treatment in primary ER + breast cancer: further results from the POETIC trial (CRUK/07/015).
(Breast Cancer Research, Springer Nature, 2023-04-12)Purpose: Ki67 assessed at diagnosis (Ki67baseline) is an important prognostic factor in primary oestrogen receptor-positive (ER +) breast cancer. Proportional change in Ki67 after 2 weeks (∆Ki672week) is associated with ... -
Equality, diversity, and inclusion in UK gastroenterology.
(The Lancet Gastroenterology & Hepatology, Elsevier., 2023-06-01)No abstract available. -
The impact of co-morbidities on cardiac rehabilitation outcomes.
(The Royal Wolverhampton NHS Trust., 2023-05-12)To explore the efficacy of exercise rehabilitation in patients with coronary heart disease plus multimorbidity attending a CR programme in Wolverhampton an area of deprivation in the West Midlands. -
The impact of co-morbidities on cardiac rehabilitation outcomes.
(The Royal Wolverhampton NHS Trust., 2023-05-12)To explore the efficacy of exercise rehabilitation in patients with coronary heart disease plus multimorbidity attending a CR programme in Wolverhampton - an area of deprivation in the West Midlands. -
Healthcare financing in Nigeria: a policy review.
(International Journal of Social Determinants of Health and Health Services, Sage., 2023-05-15)A good health financing system is crucial for the effective performance of a country's health system. Many health systems around the world, especially in lower- and middle-income countries such as Nigeria, grapple with ... -
The white-eyed blowout fracture in the child: beware of distractions.
(Journal of Surgical Case Reports, Oxford Academic., 2013-07-12)Inferior ‘trapdoor’ orbital floor fractures with muscle and soft tissue incarceration are the most common type of orbital fracture in children. Delays to treatment can lead to a significant morbidity. It has been recommended ... -
Cardiac surgery in a patient with severe thrombocytopenia: how low is too low?
(Annals of Cardiac Aaesthesia, Lippincott, Williams & Wilkins., 2013-07-16)Platelets play a very important role in hemostasis, especially after cardiac surgery. Excessive bleeding after such surgery may lead to increased need for transfusion and its incumbent increase in post-operative morbidity ... -
Do differences in female sex hormone levels contribute to gastro-oesophageal reflux disease?
(European Journal of Gastroenterology and Hepatology, Wolters Kluwer., 2013-07-01)Background Hormone replacement therapy is associated with both reflux symptoms and oesophagitis. During pregnancy, elevated sex hormones are thought to contribute to the high prevalence of reflux symptoms. Increased ... -
Retinal changes in patients with idiopathic inflammatory myopathies: a case-control study in the MyoCite cohort.
(Frontiers in Medicine, Frontiers Media, 2022-11-30)Background: Retinal changes are the window to systemic vasculature. Therefore, we explored retinal changes in patients with Idiopathic inflammatory myopathies (IIM) as a surrogate for vascular health. Methods: Adult and ... -
Lesson of the month: cytotoxic lesions of the corpus callosum (CLOCCs) in status epilepticus
(Clinical Medicine Journal, Royal College of Physicians, 2022-09-01)A 26-year-old man was diagnosed with epilepsy a few months previously and admitted with status epilepticus. Computed tomography (CT) of the brain and CT venography were unremarkable. Magnetic resonance imaging (MRI) of the ... -
Meta-analysis: The efficacy of therapeutic drug monitoring of anti-TNF-therapy in inflammatory bowel disease.
(Alimentary Pharmacology and Therapeutics, Wiley., 2022-12-09)Background and aims: This systematic review and meta-analysis aimed to determine whether the use of therapeutic drug monitoring (TDM) in inflammatory bowel disease (IBD) patients on anti-tumour necrosis factor (anti-TNF) ... -
Possible relationship between poor skin disorders prognosis and serum zinc level: a narrative review.
(Dermatology Reports, PagePress, 2022-07-06)Zinc is a trace nutrient essential for the normal growth and development of human body. The main aim was to evaluate the significant association between measured zinc status in relation to different skin disorders and their ...